Blood protein predictors of brain amyloid for enrichment in clinical trials?

BACKGROUND: Measures of neocortical amyloid burden (NAB) identify individuals who are at substantially greater risk of developing Alzheimer's disease (AD). Blood-based biomarkers predicting NAB would have great utility for the enrichment of AD clinical trials, including large-scale prevention t...

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Bibliografski detalji
Izdano u:Alzheimers Dement (Amst)
Glavni autori: Ashton, Nicholas J., Kiddle, Steven J., Graf, John, Ward, Malcolm, Baird, Alison L., Hye, Abdul, Westwood, Sarah, Wong, Karyuan Vivian, Dobson, Richard J., Rabinovici, Gil D., Miller, Bruce L., Rosen, Howard J., Torres, Andrew, Zhang, Zhanpan, Thurfjell, Lennart, Covin, Antonia, Hehir, Cristina Tan, Baker, David, Bazenet, Chantal, Lovestone, Simon
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Blood-Based Biomarker
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876903/
https://ncbi.nlm.nih.gov/pubmed/27239491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2014.11.005
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