Blood protein predictors of brain amyloid for enrichment in clinical trials?

BACKGROUND: Measures of neocortical amyloid burden (NAB) identify individuals who are at substantially greater risk of developing Alzheimer's disease (AD). Blood-based biomarkers predicting NAB would have great utility for the enrichment of AD clinical trials, including large-scale prevention t...

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Bibliographic Details
Published in:Alzheimers Dement (Amst)
Main Authors: Ashton, Nicholas J., Kiddle, Steven J., Graf, John, Ward, Malcolm, Baird, Alison L., Hye, Abdul, Westwood, Sarah, Wong, Karyuan Vivian, Dobson, Richard J., Rabinovici, Gil D., Miller, Bruce L., Rosen, Howard J., Torres, Andrew, Zhang, Zhanpan, Thurfjell, Lennart, Covin, Antonia, Hehir, Cristina Tan, Baker, David, Bazenet, Chantal, Lovestone, Simon
Format: Artigo
Language:Inglês
Published: Elsevier 2015
Subjects:
Blood-Based Biomarker
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876903/
https://ncbi.nlm.nih.gov/pubmed/27239491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2014.11.005
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