The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

The microRNA-29 (miR-29) family is among the most abundantly expressed microRNA in the pancreas and liver. Here, we investigated the function of miR-29 in glucose regulation using miR-29a/b-1 (miR-29a)-deficient mice and newly generated miR-29b-2/c (miR-29c)-deficient mice. We observed multiple inde...

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Vydáno v:Diabetes
Hlavní autoři: Dooley, James, Garcia-Perez, Josselyn E., Sreenivasan, Jayasree, Schlenner, Susan M., Vangoitsenhoven, Roman, Papadopoulou, Aikaterini S., Tian, Lei, Schonefeldt, Susann, Serneels, Lutgarde, Deroose, Christophe, Staats, Kim A., Van der Schueren, Bart, De Strooper, Bart, McGuinness, Owen P., Mathieu, Chantal, Liston, Adrian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2016
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876765/
https://ncbi.nlm.nih.gov/pubmed/26696639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0770
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