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Differentiation of G:C vs. A:T and G:C vs. G:mC Base: Pairs in the Latch Zone of Alpha-Hemolysin
The alpha-hemolysin (α-HL) nanopore can detect DNA strands under an electrophoretic force via many regions of the channel. Our laboratories previously demonstrated that trapping duplex DNA in the vestibule of wild-type α-HL under force could distinguish the presence of an abasic site compared to a G...
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| Udgivet i: | ACS Nano |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4876701/ https://ncbi.nlm.nih.gov/pubmed/26506108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b05055 |
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