BASE-EXCISION REPAIR ACTIVITY OF URACIL-DNA GLYCOSYLASE MONITORED USING THE LATCH ZONE OF α-HEMOLYSIN

Nanopores have been investigated as a simple and label-free tool to characterize DNA nucleotides when a ssDNA strand translocates through the constriction of the pore. Here, a wild-type α-hemolysin protein nanopore was used to monitor DNA repair enzyme activity based on base-specific interactions of...

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Hlavní autoři: Jin, Qian, Fleming, Aaron M., Johnson, Robert P., Ding, Yun, Burrows, Cynthia J., White, Henry S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905681/
https://ncbi.nlm.nih.gov/pubmed/24295110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja410615d
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