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Differentiation of G:C vs. A:T and G:C vs. G:mC Base: Pairs in the Latch Zone of Alpha-Hemolysin

The alpha-hemolysin (α-HL) nanopore can detect DNA strands under an electrophoretic force via many regions of the channel. Our laboratories previously demonstrated that trapping duplex DNA in the vestibule of wild-type α-HL under force could distinguish the presence of an abasic site compared to a G...

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Publicat a:ACS Nano
Autors principals: Ding, Yun, Fleming, Aaron M., White, Henry S., Burrows, Cynthia J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876701/
https://ncbi.nlm.nih.gov/pubmed/26506108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b05055
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