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Antigen Nature and Complexity Influence Human Antibody Light Chain Usage and Specificity

Human antibodies consist of a heavy chain and one of two possible light chains, kappa (κ) or lambda (λ). Here we tested how these two possible light chains influence the overall antibody response to polysaccharide and protein antigens by measuring light chain usage in human monoclonal antibodies fro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Vaccine
Egile Nagusiak: Smith, Kenneth, Shah, Hemangi, Muther, Jennifer J., Duke, Angie L., Haley, Kathleen, James, Judith A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876604/
https://ncbi.nlm.nih.gov/pubmed/27113164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.04.040
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