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Antigen Nature and Complexity Influence Human Antibody Light Chain Usage and Specificity
Human antibodies consist of a heavy chain and one of two possible light chains, kappa (κ) or lambda (λ). Here we tested how these two possible light chains influence the overall antibody response to polysaccharide and protein antigens by measuring light chain usage in human monoclonal antibodies fro...
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| Veröffentlicht in: | Vaccine |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4876604/ https://ncbi.nlm.nih.gov/pubmed/27113164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.04.040 |
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