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Immunogenicity associated with metreleptin treatment in patients with obesity or lipodystrophy
OBJECTIVE: Recombinant human leptin (metreleptin) improves glycemia and hypertriglyceridemia in patients with generalized lipodystrophy; antibody development with in vitro neutralizing activity has been reported. We aimed to characterize anti-metreleptin antibody development, including in vitro neut...
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| Gepubliceerd in: | Clin Endocrinol (Oxf) |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875885/ https://ncbi.nlm.nih.gov/pubmed/26589105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cen.12980 |
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