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Sensing bacterial infections by NAIP receptors in NLRC4 inflammasome activation
The inflammasome is an emerging new pathway in innate immune defense against microbial infection or endogenous danger signals. The inflammasome stimulates activation of inflammatory caspases, mainly caspase-1. Caspase-1 activation is responsible for processing and secretion of IL-1β and IL-18 as wel...
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| Publicado no: | Protein Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875417/ https://ncbi.nlm.nih.gov/pubmed/22426978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2028-3 |
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