The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability

Mycosin-1 protease (MycP1) is a serine protease anchored to the inner membrane of Mycobacterium tuberculosis, and is essential in virulence factor secretion through the ESX-1 type VII secretion system (T7SS). Bacterial physiology studies demonstrated that MycP1 plays a dual role in the regulation of...

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Dettagli Bibliografici
Pubblicato in:Protein Cell
Autori principali: Sun, Demeng, Liu, Qing, He, Yao, Wang, Chengliang, Wu, Fangming, Tian, Changlin, Zang, Jianye
Natura: Artigo
Lingua:Inglês
Pubblicazione: Higher Education Press 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875400/
https://ncbi.nlm.nih.gov/pubmed/24248472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-3089-7
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