Crystal structure of human Gadd45 reveals an active dimer

The human Gadd45 protein family plays critical roles in DNA repair, negative growth control, genomic stability, cell cycle checkpoints and apoptosis. Here we report the crystal structure of human Gadd45, revealing a unique dimer formed via a bundle of four parallel helices, involving the most conser...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Protein Cell
Päätekijät: Zhang, Wenzheng, Fu, Sheng, Liu, Xuefeng, Zhao, Xuelian, Zhang, Wenchi, Peng, Wei, Wu, Congying, Li, Yuanyuan, Li, Xuemei, Bartlam, Mark, Zeng, Zong-Hao, Zhan, Qimin, Rao, Zihe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Higher Education Press 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875293/
https://ncbi.nlm.nih.gov/pubmed/22058036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1090-6
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