Crystal structure of human Gadd45 reveals an active dimer

The human Gadd45 protein family plays critical roles in DNA repair, negative growth control, genomic stability, cell cycle checkpoints and apoptosis. Here we report the crystal structure of human Gadd45, revealing a unique dimer formed via a bundle of four parallel helices, involving the most conser...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Cell
Main Authors: Zhang, Wenzheng, Fu, Sheng, Liu, Xuefeng, Zhao, Xuelian, Zhang, Wenchi, Peng, Wei, Wu, Congying, Li, Yuanyuan, Li, Xuemei, Bartlam, Mark, Zeng, Zong-Hao, Zhan, Qimin, Rao, Zihe
Format: Artigo
Jezik:Inglês
Izdano: Higher Education Press 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875293/
https://ncbi.nlm.nih.gov/pubmed/22058036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1090-6
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