Crystal structure of human Gadd45 reveals an active dimer

The human Gadd45 protein family plays critical roles in DNA repair, negative growth control, genomic stability, cell cycle checkpoints and apoptosis. Here we report the crystal structure of human Gadd45, revealing a unique dimer formed via a bundle of four parallel helices, involving the most conser...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Protein Cell
Hlavní autoři: Zhang, Wenzheng, Fu, Sheng, Liu, Xuefeng, Zhao, Xuelian, Zhang, Wenchi, Peng, Wei, Wu, Congying, Li, Yuanyuan, Li, Xuemei, Bartlam, Mark, Zeng, Zong-Hao, Zhan, Qimin, Rao, Zihe
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875293/
https://ncbi.nlm.nih.gov/pubmed/22058036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1090-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky