Crystal structure of human Gadd45 reveals an active dimer

The human Gadd45 protein family plays critical roles in DNA repair, negative growth control, genomic stability, cell cycle checkpoints and apoptosis. Here we report the crystal structure of human Gadd45, revealing a unique dimer formed via a bundle of four parallel helices, involving the most conser...

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書目詳細資料
發表在:Protein Cell
Main Authors: Zhang, Wenzheng, Fu, Sheng, Liu, Xuefeng, Zhao, Xuelian, Zhang, Wenchi, Peng, Wei, Wu, Congying, Li, Yuanyuan, Li, Xuemei, Bartlam, Mark, Zeng, Zong-Hao, Zhan, Qimin, Rao, Zihe
格式: Artigo
語言:Inglês
出版: Higher Education Press 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875293/
https://ncbi.nlm.nih.gov/pubmed/22058036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1090-6
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