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Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases

Azoreductases are involved in the bioremediation by bacteria of azo dyes found in waste water. In the gut flora, they activate azo pro-drugs, which are used for treatment of inflammatory bowel disease, releasing the active component 5-aminosalycilic acid. The bacterium P. aeruginosa has three azored...

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Veröffentlicht in:Protein Cell
Hauptverfasser: Ryan, Ali, Wang, Chan-Ju, Laurieri, Nicola, Westwood, Isaac, Sim, Edith
Format: Artigo
Sprache:Inglês
Veröffentlicht: Higher Education Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875192/
https://ncbi.nlm.nih.gov/pubmed/21203919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0090-2
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