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Quantitative Analyses of Core Promoters Enable Precise Engineering of Regulated Gene Expression in Mammalian Cells

Inducible transcription systems play a crucial role in a wide array of synthetic biology circuits. However, the majority of inducible promoters are constructed from a limited set of tried-and-true promoter parts, which are susceptible to common shortcomings such as high basal expression levels (i.e....

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Vydáno v:ACS Synth Biol
Hlavní autoři: Ede, Christopher, Chen, Ximin, Lin, Meng-Yin, Chen, Yvonne Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874895/
https://ncbi.nlm.nih.gov/pubmed/26883397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.5b00266
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