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Conditional DNA repair mutants enable highly precise genome engineering
Oligonucleotide-mediated multiplex genome engineering is an important tool for bacterial genome editing. The efficient application of this technique requires the inactivation of the endogenous methyl-directed mismatch repair system that in turn leads to a drastically elevated genomic mutation rate a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005651/ https://ncbi.nlm.nih.gov/pubmed/24500200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku105 |
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