Conditional DNA repair mutants enable highly precise genome engineering

Oligonucleotide-mediated multiplex genome engineering is an important tool for bacterial genome editing. The efficient application of this technique requires the inactivation of the endogenous methyl-directed mismatch repair system that in turn leads to a drastically elevated genomic mutation rate a...

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Bibliografske podrobnosti
Main Authors: Nyerges, Ákos, Csörgő, Bálint, Nagy, István, Latinovics, Dóra, Szamecz, Béla, Pósfai, György, Pál, Csaba
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005651/
https://ncbi.nlm.nih.gov/pubmed/24500200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku105
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