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A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species

Currently available tools for multiplex bacterial genome engineering are optimized for a few laboratory model strains, demand extensive prior modification of the host strain, and lead to the accumulation of numerous off-target modifications. Building on prior development of multiplex automated genom...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Nyerges, Ákos, Csörgő, Bálint, Nagy, István, Bálint, Balázs, Bihari, Péter, Lázár, Viktória, Apjok, Gábor, Umenhoffer, Kinga, Bogos, Balázs, Pósfai, György, Pál, Csaba
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780621/
https://ncbi.nlm.nih.gov/pubmed/26884157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520040113
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