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A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species
Currently available tools for multiplex bacterial genome engineering are optimized for a few laboratory model strains, demand extensive prior modification of the host strain, and lead to the accumulation of numerous off-target modifications. Building on prior development of multiplex automated genom...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780621/ https://ncbi.nlm.nih.gov/pubmed/26884157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520040113 |
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