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Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations

Multidrug-resistant clinical isolates are common in certain pathogens, but rare in others. This pattern may be due to the fact that mutations shaping resistance have species-specific effects. To investigate this issue, we transferred a range of resistance-conferring mutations and a full resistance g...

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Publicat a:Mol Biol Evol
Autors principals: Apjok, Gábor, Boross, Gábor, Nyerges, Ákos, Fekete, Gergely, Lázár, Viktória, Papp, Balázs, Pál, Csaba, Csörgő, Bálint
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657729/
https://ncbi.nlm.nih.gov/pubmed/31058961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz109
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