Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance

Antibiotic development is frequently plagued by the rapid emergence of drug resistance. However, assessing the risk of resistance development in the preclinical stage is difficult. Standard laboratory evolution approaches explore only a small fraction of the sequence space and fail to identify excee...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Nyerges, Ákos, Csörgő, Bálint, Draskovits, Gábor, Kintses, Bálint, Szili, Petra, Ferenc, Györgyi, Révész, Tamás, Ari, Eszter, Nagy, István, Bálint, Balázs, Vásárhelyi, Bálint Márk, Bihari, Péter, Számel, Mónika, Balogh, Dávid, Papp, Henrietta, Kalapis, Dorottya, Papp, Balázs, Pál, Csaba
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016788/
https://ncbi.nlm.nih.gov/pubmed/29871954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801646115
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares