טוען...
ATXN7L3 AND ENY2 COORDINATE ACTIVITY OF MULTIPLE H2B DEUBIQUITINASES IMPORTANT FOR CELLULAR PROLIFERATION AND TUMOR GROWTH
Histone H2B monoubiquitination (H2Bub1) is centrally involved in gene regulation. The deubiquitination module (DUBm) of the SAGA complex is a major regulator of global H2Bub1 levels, and components of this DUBm are linked to both neurodegenerative diseases and cancer. Unexpectedly, we find that abla...
שמור ב:
| הוצא לאור ב: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874879/ https://ncbi.nlm.nih.gov/pubmed/27132940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.030 |
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