USP44 IS AN INTEGRAL COMPONENT OF N-COR THAT CONTRIBUTES TO GENE REPRESSION BY DEUBIQUITINATING HISTONE H2B

Decreased expression of the USP44 deubiquitinase has been associated with global increases in H2Bub1 levels during mES cell differentiation. However, whether USP44 directly deubiquitinates histone H2B or how its activity is targeted to chromatin are not known. Here, we identified USP44 as an integra...

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Publicado en:Cell Rep
Autores principales: Lan, Xianjiang, Atanassov, Boyko S., Li, Wenqian, Zhang, Ying, Florens, Laurence, Mohan, Ryan D., Galardy, Paul J., Washburn, Michael P., Workman, Jerry L., Dent, Sharon Y. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131803/
https://ncbi.nlm.nih.gov/pubmed/27880911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.076
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