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USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1
Ubiquitin-specific protease 22 (USP22) edits the histone code by deubiquitinating H2A and H2B as part of the mammalian SAGA (Spt-Ada-Gcn5) complex, and is required for transcriptional regulation and normal cell-cycle progression. Here, we show that USP22 affects the expression of p21 by altering far...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166460/ https://ncbi.nlm.nih.gov/pubmed/21779003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.140 |
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