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Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas

Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent bacterial strains and species. Whether these resistance mutations are having parallel effects on fitness across bacterial taxa, however, is unclear. Thi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Biol Sci
Egile Nagusiak: Vogwill, T., Kojadinovic, M., MacLean, R. C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874708/
https://ncbi.nlm.nih.gov/pubmed/27170722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2016.0151
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