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Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas

Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent bacterial strains and species. Whether these resistance mutations are having parallel effects on fitness across bacterial taxa, however, is unclear. Thi...

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Detalles Bibliográficos
Publicado en:Proc Biol Sci
Autores principales: Vogwill, T., Kojadinovic, M., MacLean, R. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874708/
https://ncbi.nlm.nih.gov/pubmed/27170722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2016.0151
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