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Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas
Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent bacterial strains and species. Whether these resistance mutations are having parallel effects on fitness across bacterial taxa, however, is unclear. Thi...
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| 出版年: | Proc Biol Sci |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Royal Society
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874708/ https://ncbi.nlm.nih.gov/pubmed/27170722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2016.0151 |
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