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Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas

Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent bacterial strains and species. Whether these resistance mutations are having parallel effects on fitness across bacterial taxa, however, is unclear. Thi...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: Vogwill, T., Kojadinovic, M., MacLean, R. C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874708/
https://ncbi.nlm.nih.gov/pubmed/27170722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2016.0151
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