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Age-related Decline in Natural IgM Function: Diversification and Selection of the B-1a Cell Pool with Age
Streptococcus pneumoniae is the most common cause of pneumonia, which claims the lives of people over the age of 65 seven times more frequently than those aged 5–49. B-1a cells provide immediate and essential protection from S. pneumoniae through production of natural immunoglobulin, which has minim...
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| Gepubliceerd in: | J Immunol |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874569/ https://ncbi.nlm.nih.gov/pubmed/27183643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600073 |
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