Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis

Maintenance of myeloid cell homeostasis requires continuous turnover of phagocytes from the bloodstream, yet whether environmental signals influence phagocyte longevity in the absence of inflammation remains unknown. Here, we show that the gut microbiota regulates the steady-state cellular lifespan...

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Udgivet i:Blood
Main Authors: Hergott, Christopher B., Roche, Aoife M., Tamashiro, Edwin, Clarke, Thomas B., Bailey, Aubrey G., Laughlin, Alice, Bushman, Frederic D., Weiser, Jeffrey N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Phagocytes, Granulocytes, and Myelopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874226/
https://ncbi.nlm.nih.gov/pubmed/26989200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-675173
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