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Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

Phagocytes orchestrate acute inflammation and host defense. Here we carried out lipid mediator (LM) metabololipidomics profiling distinct phagocytes: neutrophils (PMN), apoptotic PMN, and macrophages. Efferocytosis increased specialized pro-resolving mediator (SPM) biosynthesis, including Resolvin D...

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Detalhes bibliográficos
Main Authors: Dalli, Jesmond, Serhan, Charles N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471524/
https://ncbi.nlm.nih.gov/pubmed/22904297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-423525
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