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The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes
A subset of inflammatory-response NF-κB target genes is activated immediately following pro-inflammatory signal. Here we followed the kinetics of primary transcript accumulation after NF-κB activation when the elongation factor Spt5 is knocked down. While elongation rate is unchanged, the transcript...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873663/ https://ncbi.nlm.nih.gov/pubmed/27180651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11547 |
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