The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation

TFIIE and the archaeal homolog TFE enhance DNA strand separation of eukaryotic RNAPII and the archaeal RNAP during transcription initiation by an unknown mechanism. We have developed a fluorescently labeled recombinant M. jannaschii RNAP system to probe the archaeal transcription initiation complex,...

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Detalhes bibliográficos
Main Authors: Grohmann, Dina, Nagy, Julia, Chakraborty, Anirban, Klose, Daniel, Fielden, Daniel, Ebright, Richard H., Michaelis, Jens, Werner, Finn
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223566/
https://ncbi.nlm.nih.gov/pubmed/21777815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.030
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