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The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes

A subset of inflammatory-response NF-κB target genes is activated immediately following pro-inflammatory signal. Here we followed the kinetics of primary transcript accumulation after NF-κB activation when the elongation factor Spt5 is knocked down. While elongation rate is unchanged, the transcript...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Diamant, Gil, Bahat, Anat, Dikstein, Rivka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873663/
https://ncbi.nlm.nih.gov/pubmed/27180651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11547
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