Comparison of Antibodies with Amylase Activity from Cerebrospinal Fluid and Serum of Patients with Multiple Sclerosis

We have recently shown that IgGs from serum and cerebrospinal fluid (CSF) of MS patients are active in hydrolysis of DNA and myelin basic protein. According to literature data, anti-DNA and anti-MBP abzymes may promote important neuropathologic mechanisms in this chronic inflammatory disorder and in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Doronin, Vasilii B., Parkhomenko, Taisiya A., Castellazzi, Massimiliano, Cesnik, Edward, Buneva, Valentina N., Granieri, Enrico, Nevinsky, Georgy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873009/
https://ncbi.nlm.nih.gov/pubmed/27196086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154688
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