Comparison of DNA-Hydrolyzing Antibodies from the Cerebrospinal Fluid and Serum of Patients with Multiple Sclerosis

It was found that high-affinity anti-DNA antibodies were one of the major components of the intrathecal IgG response in multiple sclerosis (MS) patients [Williamson et al., PNAS, 2001]. Recently we have shown that IgGs from the sera of MS patients are active in the hydrolysis of DNA. Here we have sh...

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Autori principali: Parkhomenko, Taisiya A., Doronin, Vasilii B., Castellazzi, Massimiliano, Padroni, Marina, Pastore, Michela, Buneva, Valentina N., Granieri, Enrico, Nevinsky, Georgy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988009/
https://ncbi.nlm.nih.gov/pubmed/24736683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093001
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