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Antibodies from the Sera of Multiple Sclerosis Patients Efficiently Hydrolyze Five Histones

It is known that intranuclear histones can be pernicious after entering to the extracellular space. In addition, the immunization of animals with exogenous histones leads to systemic inflammatory and toxic reactions. Abzymes—autoantibodies with enzymatic activities—are the distinctive feature of aut...

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Detalles Bibliográficos
Publicado en:Biomolecules
Main Authors: Baranova, Svetlana V., Mikheeva, Elena V., Buneva, Valentina N., Nevinsky, Georgy A.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920934/
https://ncbi.nlm.nih.gov/pubmed/31731780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110741
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