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Antibodies from the Sera of Multiple Sclerosis Patients Efficiently Hydrolyze Five Histones

It is known that intranuclear histones can be pernicious after entering to the extracellular space. In addition, the immunization of animals with exogenous histones leads to systemic inflammatory and toxic reactions. Abzymes—autoantibodies with enzymatic activities—are the distinctive feature of aut...

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Dades bibliogràfiques
Publicat a:Biomolecules
Autors principals: Baranova, Svetlana V., Mikheeva, Elena V., Buneva, Valentina N., Nevinsky, Georgy A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920934/
https://ncbi.nlm.nih.gov/pubmed/31731780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110741
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