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Antibodies from the Sera of Multiple Sclerosis Patients Efficiently Hydrolyze Five Histones

It is known that intranuclear histones can be pernicious after entering to the extracellular space. In addition, the immunization of animals with exogenous histones leads to systemic inflammatory and toxic reactions. Abzymes—autoantibodies with enzymatic activities—are the distinctive feature of aut...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Baranova, Svetlana V., Mikheeva, Elena V., Buneva, Valentina N., Nevinsky, Georgy A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920934/
https://ncbi.nlm.nih.gov/pubmed/31731780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110741
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