Comparison of Antibodies with Amylase Activity from Cerebrospinal Fluid and Serum of Patients with Multiple Sclerosis

We have recently shown that IgGs from serum and cerebrospinal fluid (CSF) of MS patients are active in hydrolysis of DNA and myelin basic protein. According to literature data, anti-DNA and anti-MBP abzymes may promote important neuropathologic mechanisms in this chronic inflammatory disorder and in...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Doronin, Vasilii B., Parkhomenko, Taisiya A., Castellazzi, Massimiliano, Cesnik, Edward, Buneva, Valentina N., Granieri, Enrico, Nevinsky, Georgy A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873009/
https://ncbi.nlm.nih.gov/pubmed/27196086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154688
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