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Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes
AIMS: 3′,5′-Cyclic adenosine monophosphate (cAMP) signals in the heart are often confined to concentration microdomains shaped by cAMP diffusion and enzymatic degradation. While the importance of phosphodiesterases (degradative enzymes) in sculpting cAMP microdomains is well established in cardiomyo...
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| 出版年: | Cardiovasc Res |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872880/ https://ncbi.nlm.nih.gov/pubmed/27089919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw080 |
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