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Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite derived phospholipase
Atopic dermatitis is a common pruritic skin disease in which barrier dysfunction and cutaneous inflammation play a role in pathogenesis. Mechanisms underlying the associated inflammation are not fully understood, and while CD1a-expressing Langerhans cells are known to be enriched within lesions, the...
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| Veröffentlicht in: | Sci Transl Med |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872823/ https://ncbi.nlm.nih.gov/pubmed/26865566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad6833 |
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