Orchestrated control of filaggrin–actin scaffolds underpins cornification

Epidermal stratification critically depends on keratinocyte differentiation and programmed death by cornification, leading to formation of a protective skin barrier. Cornification is dynamically controlled by the protein filaggrin, rapidly released from keratohyalin granules (KHGs). However, the mec...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gutowska-Owsiak, Danuta, de La Serna, Jorge Bernardino, Fritzsche, Marco, Naeem, Aishath, Podobas, Ewa I., Leeming, Michael, Colin-York, Huw, O’Shaughnessy, Ryan, Eggeling, Christian, Ogg, Graham S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854575/
https://ncbi.nlm.nih.gov/pubmed/29545605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0407-2
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