Comparison of liver oncogenic potential among human RAS isoforms

Mutation in one of three RAS genes (i.e., HRAS, KRAS, and NRAS) leading to constitutive activation of RAS signaling pathways is considered a key oncogenic event in human carcinogenesis. Whether activated RAS isoforms possess different oncogenic potentials remains an unresolved question. Here, we com...

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Vydáno v:Oncotarget
Hlavní autoři: Chung, Sook In, Moon, Hyuk, Ju, Hye-Lim, Kim, Dae Yeong, Cho, Kyung Joo, Ribback, Silvia, Dombrowski, Frank, Calvisi, Diego F., Ro, Simon Weonsang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872791/
https://ncbi.nlm.nih.gov/pubmed/26799184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6931
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