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Comparison of liver oncogenic potential among human RAS isoforms

Mutation in one of three RAS genes (i.e., HRAS, KRAS, and NRAS) leading to constitutive activation of RAS signaling pathways is considered a key oncogenic event in human carcinogenesis. Whether activated RAS isoforms possess different oncogenic potentials remains an unresolved question. Here, we com...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Chung, Sook In, Moon, Hyuk, Ju, Hye-Lim, Kim, Dae Yeong, Cho, Kyung Joo, Ribback, Silvia, Dombrowski, Frank, Calvisi, Diego F., Ro, Simon Weonsang
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872791/
https://ncbi.nlm.nih.gov/pubmed/26799184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6931
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