Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor

Genetically engineered mouse cancer models allow tumors to be imaged in vivo via co-expression of a reporter gene with a tumor-initiating gene. However, differential transcriptional and translational regulation between the tumor-initiating gene and the reporter gene can result in inconsistency betwe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Ju, Hye-Lim, Calvisi, Diego F., Moon, Hyuk, Baek, Sinhwa, Ribback, Silvia, Dombrowski, Frank, Cho, Kyung Joo, Chung, Sook In, Han, Kwang-Hyub, Ro, Simon Weonsang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306974/
https://ncbi.nlm.nih.gov/pubmed/25623590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08053
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg