Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor

Genetically engineered mouse cancer models allow tumors to be imaged in vivo via co-expression of a reporter gene with a tumor-initiating gene. However, differential transcriptional and translational regulation between the tumor-initiating gene and the reporter gene can result in inconsistency betwe...

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Publicado no:Sci Rep
Main Authors: Ju, Hye-Lim, Calvisi, Diego F., Moon, Hyuk, Baek, Sinhwa, Ribback, Silvia, Dombrowski, Frank, Cho, Kyung Joo, Chung, Sook In, Han, Kwang-Hyub, Ro, Simon Weonsang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306974/
https://ncbi.nlm.nih.gov/pubmed/25623590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08053
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