Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background

BACKGROUND: Liver fibrosis and its end-stage disease, cirrhosis, are major risk factors for hepatocellular carcinoma (HCC) and present in 80 to 90 % of patients with HCC. Current genetically engineered mouse models for HCC, however, generally do not feature liver fibrosis, which is a critical discre...

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Библиографические подробности
Опубликовано в: :BMC Gastroenterol
Главные авторы: Chung, Sook In, Moon, Hyuk, Kim, Dae Yeong, Cho, Kyung Joo, Ju, Hye-Lim, Kim, Do Young, Ahn, Sang Hoon, Han, Kwang-Hyub, Ro, Simon Weonsang
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731926/
https://ncbi.nlm.nih.gov/pubmed/26821924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-016-0423-6
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