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G(q)-dependent signalling by the lysophosphatidic acid receptor LPA(3) in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA

The present study characterized the signalling pathways initiated by the bioactive lipid, LPA (lysophosphatidic acid) in smooth muscle. Expression of LPA(3) receptors, but not LPA(1) and LPA(2), receptors was demonstrated by Western blot analysis. LPA stimulated phosphoinositide hydrolysis, PKC (pro...

詳細記述

保存先:
書誌詳細
出版年:Biochem J
主要な著者: Sriwai, Wimolpak, Zhou, Huiping, Murthy, Karnam S.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872639/
https://ncbi.nlm.nih.gov/pubmed/18237278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/bj20071299
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