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The Branched Short Chain Fatty Acid Isovaleric Acid Causes Colonic Smooth Muscle Relaxation via cAMP/PKA Pathway

BACKGROUND. Isovaleric Acid (IVA) is a 5-carbon branched chain fatty acid present in fermented foods and produced in the colon by bacterial fermentation of leucine. We previously reported that the shorter, straight chain fatty acids acetate, propionate and butyrate, differentially affect colonic mot...

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Detalhes bibliográficos
Publicado no:Dig Dis Sci
Main Authors: Blakeney, Bryan A., Crowe, Molly S., Mahavadi, Sunila, Murthy, Karnam S., Grider, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499669/
https://ncbi.nlm.nih.gov/pubmed/30560338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-018-5417-5
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