The Branched Short Chain Fatty Acid Isovaleric Acid Causes Colonic Smooth Muscle Relaxation via cAMP/PKA Pathway

BACKGROUND. Isovaleric Acid (IVA) is a 5-carbon branched chain fatty acid present in fermented foods and produced in the colon by bacterial fermentation of leucine. We previously reported that the shorter, straight chain fatty acids acetate, propionate and butyrate, differentially affect colonic mot...

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Vydáno v:Dig Dis Sci
Hlavní autoři: Blakeney, Bryan A., Crowe, Molly S., Mahavadi, Sunila, Murthy, Karnam S., Grider, John R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499669/
https://ncbi.nlm.nih.gov/pubmed/30560338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-018-5417-5
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